What is the difference between the mattress pad and mattress protector? January 15, 2021 15:02 Updated The Organic Mattress Pad is 100% organic and provides natural protection against spills and stains without the use of polyurethane materials. The Waterproof Mattress Protector uses this polyurethane layer to provide waterproof protection. Related articles Is the mattress pad machine washable? Does the mattress pad change the feel of my mattress? Does the mattress pad sleep hot? Does the Birch Mattress require a foundation? Can I wash my Plush Organic Mattress Topper?