How long will my mattress protector last? January 15, 2021 14:56 Updated With normal use and regular washing the mattress protector can provide durable protection for five years or longer. Related articles How does the mattress protector work with my fitted sheet and other toppers? How does the mattress protector fit on my mattress? Is the mattress pad waterproof? Should I ever rotate my Birch Mattress? Is the mattress protector waterproof?